Koji Kawakami Selected Research

Interleukin-13 Receptors (Interleukin 13 Receptor)

1/2019	A novel interleukin-13 receptor alpha 2-targeted hybrid peptide for effective glioblastoma therapy.
9/2005	Combined effects of radiation and interleukin-13 receptor-targeted cytotoxin on glioblastoma cell lines.
4/2005	Cancer gene therapy utilizing interleukin-13 receptor alpha2 chain.
12/2004	Distribution kinetics of targeted cytotoxin in glioma by bolus or convection-enhanced delivery in a murine model.
9/2004	Analysis of interleukin-13 receptor alpha2 expression in human pediatric brain tumors.
5/2004	Mechanism of action of interleukin-13 antagonist (IL-13E13K) in cells expressing various types of IL-4R.
12/2003	Interleukin-13 receptor alpha2 chain in human head and neck cancer serves as a unique diagnostic marker.
1/2003	Tumor regression mechanisms by IL-13 receptor-targeted cancer therapy involve apoptotic pathways.
12/2002	IL-13 receptor-targeted cytotoxin cancer therapy leads to complete eradication of tumors with the aid of phagocytic cells in nude mice model of human cancer.
10/2002	Intratumor administration of interleukin 13 receptor-targeted cytotoxin induces apoptotic cell death in human malignant glioma tumor xenografts.

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Koji Kawakami Research Topics

Disease

73	Neoplasms (Cancer) 02/2021 - 01/2002
10	Glioblastoma (Glioblastoma Multiforme) 02/2019 - 01/2002
10	Pancreatic Neoplasms (Pancreatic Cancer) 05/2015 - 07/2002
9	Alzheimer Disease (Alzheimer's Disease) 01/2020 - 08/2010
8	Infections 07/2022 - 08/2005
8	Head and Neck Neoplasms (Head and Neck Cancer) 01/2019 - 02/2002
8	Breast Neoplasms (Breast Cancer) 05/2018 - 05/2003
6	Glioma (Gliomas) 12/2013 - 10/2002
5	Diabetes Mellitus 07/2022 - 05/2013
5	Asthma (Bronchial Asthma) 01/2022 - 05/2004
5	Hemorrhage 01/2022 - 10/2015
5	Vomiting 07/2021 - 04/2012
5	Brain Neoplasms (Brain Tumor) 02/2010 - 01/2002
4	Human Influenza (Influenza) 07/2022 - 01/2011
4	Type 2 Diabetes Mellitus (MODY) 01/2022 - 02/2013
4	Colorectal Neoplasms (Colorectal Cancer) 02/2021 - 01/2016
4	Carcinoma (Carcinomatosis) 01/2016 - 03/2003
4	Squamous Cell Carcinoma of Head and Neck 06/2013 - 01/2002
3	Pain (Aches) 07/2022 - 01/2016
3	Cardiovascular Diseases (Cardiovascular Disease) 01/2022 - 05/2013
3	Stomach Neoplasms (Stomach Cancer) 07/2021 - 01/2011
3	Nausea 07/2021 - 04/2012
3	Out-of-Hospital Cardiac Arrest 03/2021 - 01/2019
3	Parkinson Disease (Parkinson's Disease) 07/2019 - 01/2007
3	Dementia (Dementias) 07/2019 - 01/2018
3	Kaposi Sarcoma (Kaposi's Sarcoma) 04/2005 - 01/2002
2	Hernia (Hernias) 07/2022 - 12/2019
2	Atopic Dermatitis (Atopic Eczema) 03/2022 - 10/2021
2	Kidney Diseases (Kidney Disease) 01/2022 - 07/2014
2	Respiratory Tract Infections (Respiratory Tract Infection) 11/2021 - 01/2018
2	Hypertension (High Blood Pressure) 10/2021 - 05/2013
2	Down Syndrome (Down's Syndrome) 01/2021 - 06/2020
2	Premature Birth (Birth, Premature) 01/2021 - 12/2019
2	Congenital Heart Defects (Congenital Heart Defect) 01/2021 - 06/2020
2	Lung Diseases (Lung Disease) 01/2021 - 12/2019
2	Sepsis (Septicemia) 07/2020 - 06/2019
2	MINOCA 05/2020 - 01/2020
2	Hearing Loss (Hearing Impairment) 01/2020 - 01/2018
2	Chronic Kidney Failure (Chronic Renal Failure) 01/2020 - 06/2009
2	Anemia 12/2018 - 01/2017
2	Lung Neoplasms (Lung Cancer) 01/2018 - 11/2002
2	Neuralgia (Stump Neuralgia) 01/2018 - 01/2016
2	Multiple System Atrophy 01/2018 - 10/2011

Drug/Important Bio-Agent (IBA)

29	Cytotoxins (Cytolysins)IBA 03/2012 - 01/2002
25	Peptides (Polypeptides)IBA 01/2019 - 01/2011
20	Interleukin-13IBA 06/2007 - 02/2002
16	Pharmaceutical PreparationsIBA 06/2020 - 01/2002
16	Proteins (Proteins, Gene)FDA Link 02/2019 - 01/2002
13	Interleukin-13 Receptors (Interleukin 13 Receptor)IBA 01/2019 - 02/2002
12	ExotoxinsIBA 12/2008 - 02/2002
11	Interleukin-4 Receptors (Interleukin 4 Receptor)IBA 01/2014 - 01/2002
10	Interleukin-4 (Interleukin 4)IBA 12/2008 - 01/2002
7	Anti-Bacterial Agents (Antibiotics)IBA 06/2022 - 01/2017
6	InterleukinsIBA 01/2006 - 06/2002
5	ErbB Receptors (EGF Receptor)IBA 03/2016 - 03/2011
5	Protein Disulfide-IsomerasesIBA 07/2014 - 08/2010
5	Nitric Oxide (Nitrogen Monoxide)FDA Link 10/2011 - 10/2002
4	Tobacco Smoke Pollution (Passive Smoking)IBA 01/2022 - 10/2015
4	AntiemeticsIBA 07/2021 - 04/2012
4	Amino Acids FDA Link 01/2019 - 03/2011
4	CytokinesIBA 01/2019 - 06/2002
4	EGFR-lytic peptideIBA 08/2013 - 03/2011
4	IL13-PE38IBA 08/2006 - 02/2002
3	Antiviral Agents (Antivirals)IBA 07/2022 - 01/2016
3	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 01/2018
3	Cisplatin (Platino)FDA LinkGeneric 07/2021 - 08/2002
3	regorafenibIBA 02/2021 - 01/2019
3	Palivizumab FDA Link 01/2021 - 04/2014
3	Antipsychotic Agents (Antipsychotics)IBA 09/2020 - 01/2018
3	Proton Pump InhibitorsIBA 01/2018 - 02/2015
3	Glutathione (Reduced Glutathione)IBA 03/2017 - 07/2014
3	4-cresol (p-cresol)IBA 01/2014 - 06/2009
3	Immunotoxins (Immunotoxin)IBA 03/2012 - 12/2008
3	AntigensIBA 08/2006 - 04/2005
3	Cytokine Receptors (Cytokine Receptor)IBA 05/2005 - 08/2002
3	Recombinant Fusion ProteinsIBA 08/2004 - 05/2003
2	baloxavirIBA 07/2022 - 01/2021
2	Indicators and Reagents (Reagents)IBA 10/2021 - 08/2002
2	trifluridine tipiracil drug combinationIBA 02/2021 - 12/2020
2	Anticonvulsants (Antiepileptic Drugs)IBA 01/2021 - 01/2016
2	Adrenal Cortex Hormones (Corticosteroids)IBA 07/2020 - 01/2010
2	InterferonsIBA 05/2020 - 08/2002
2	SodiumIBA 01/2020 - 01/2018
2	DisulfidesIBA 02/2019 - 05/2015
2	Antidepressive Agents (Antidepressants)IBA 01/2019 - 01/2016
2	TeaIBA 09/2018 - 01/2016
2	LipidsIBA 09/2018 - 02/2013
2	LuciferasesIBA 02/2018 - 01/2016
2	SynucleinsIBA 01/2018 - 10/2011

Therapy/Procedure

40	Therapeutics 06/2022 - 01/2002
10	Drug Therapy (Chemotherapy) 07/2021 - 04/2012
5	Injections 03/2013 - 07/2002
4	Intravenous Administration 01/2014 - 08/2011
3	Length of Stay 07/2022 - 02/2017
3	Immunotherapy 12/2011 - 02/2002
2	Induced Hypothermia 03/2021 - 01/2019
2	Enteral Nutrition (Feeding, Tube) 03/2021 - 01/2019
2	Tracheotomy 02/2021 - 12/2019
2	Tonsillectomy 11/2019 - 01/2018
2	Adjuvant Chemotherapy 05/2018 - 01/2017